Pre-emptive pharmacogenetic (PGx) testing using a multiple gene panel to guide treatment and reduce adverse drug reactions

Topic Status Complete

Pharmacogenetics (also referred to as pharmacogenomics; PGx) is the study of how a person's genes affect their response to medications. Differences in genes may result in a particular medicine being effective for some people, but not others. Equally, it may be the reason that some people experience side effects (or adverse reactions) to a medicine, whilst others do not.



Health Technology Wales researchers searched for evidence on the clinical and cost effectiveness of pre-emptive testing using a PGx panel to guide treatment and reduce adverse drug reactions.


The HTW Assessment Group decided not to progress this topic further due to the lack of evidence of effectiveness at present.

Topic Exploration Report

TER465 09.2023

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