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Completed and ongoing appraisals topics are listed below. Topics that were not accepted onto the appraisal work programme are also listed with the Topic Exploration Report (these do not include Evidence Appraisal Reports or guidance). Learn more about our appraisal process here.

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March 2024

Intensive Family Preservation Programmes (IFPP)

Intensive Family Preservation Programmes (IFPP) for families in crisis, where there is an imminent risk of out-of-home placement or children…
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March 2024

Video feedback interventions

Video feedback interventions to improve communication within family relationships and support children at risk
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March 2024

Liposuction for the treatment of chronic lymphoedema

Liposuction for the treatment of chronic lymphoedema
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January 2024

Digital wound management tools

Digital tools for the monitoring and management of wounds.
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January 2024

Low energy contact X-ray brachytherapy (CXB)

Low energy contact X-ray brachytherapy (CXB) for the treatment of early stage rectal cancer
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January 2024

Robot-assisted thoracic surgery

Robot-assisted thoracic surgery.
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December 2023

Radiofrequency renal denervation

Renal denervation to treat people with resistant hypertension
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December 2023

Solution-focused assessment tools

Solution-focused assessment tools for improving the treatment of people with severe mental illness within secondary mental health services.
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December 2023

Percutaneous implantation of pulmonary artery pressure sensors

Percutaneous implantation of pulmonary artery pressure sensors for monitoring treatment of chronic heart failure.
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November 2023

Multi-grip upper limb prosthetics

Multi-grip myoelectric upper-limb prosthetics.
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September 2023

Myopia-control contact lenses and spectacles

Myopia-control contact lenses and spectacles to slow the progression of myopia in children and adolescents.
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June 2023

Wearable cardioverter defibrillators

Wearable cardioverter defibrillators for people at risk of cardiac death
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March 2023

Photobiomodulation

Photobiomodulation for the prevention and treatment of oral mucositis associated with cancer treatment
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December 2022

Virtual reality distraction therapy

Virtual reality therapy for the management of procedure-related pain.
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November 2022

Continuous topical oxygen therapy

Continuous topical oxygen therapy to treat people with chronic non-healing and complex diabetic foot ulcers
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October 2022

Left atrial appendage occlusion in patients with atrial fibrillation

Left atrial appendage occlusion in patients with atrial fibrillation
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July 2022

Outpatient laryngeal biopsy

Laryngeal biopsies in the outpatient setting in people with suspected head and neck dysplasia/cancer
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July 2022

Closed loop systems

Closed loop systems for the management of type 1 diabetes
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June 2022

Stereotactic ablative radiotherapy (SABR)

Stereotactic ablative radiotherapy (SABR) for the treatment of renal cell carcinoma
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May 2022

Video laryngoscopes

Video laryngoscopes for use in pre-hospital care.
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May 2022

Electronic blood management systems

Electronic blood management systems for blood transfusions
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May 2022

Extreme HypoFractionated Radiotherapy (EHFRT)

Extreme HypoFractionated Radiotherapy (EHFRT) for localised prostate cancer
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March 2022

Convalescent Plasma Therapy for the Treatment of COVID-19

Convalescent plasma therapy for people with COVID-19
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February 2022

Transcranial magnetic stimulation

Transcranial magnetic stimulation for the treatment of depression
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November 2021

Strategies for Relatives (START) intervention

Strategies for Relatives (START) intervention to improve the mental health of carers of people with dementia
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November 2021

Natriuretic peptides to rule-in and rule-out a diagnosis of acute heart failure

Natriuretic peptides to rule-in and rule-out a diagnosis of acute heart failure in adults in the emergency department setting
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September 2021

FreeStyle Libre flash glucose monitoring

FreeStyle Libre flash glucose monitoring for the management of diabetes.
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July 2021

Haemodialysis antimicrobial barrier caps (ClearGuard)

Antimicrobial barrier caps for use with haemodialysis catheter hubs to reduce catheter-related bloodstream infections.
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May 2021

Handheld single lead electrocardiogram devices

Handheld single lead electrocardiogram devices to detect atrial fibrillation in older adults and those with intermittent episodes
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May 2021

Oscillating positive expiratory pressure devices

Oscillating positive expiratory pressure devices for airway clearance in chronic hypersecretory lung conditions.
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May 2021

Extracorporeal shockwave therapy

Extracorporeal shockwave therapy for the treatment of musculoskeletal conditions.
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May 2021

Corneal cross-linking

Corneal crosslinking to treat adults and children with keratoconus
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May 2021

Point-of-care ultrasound to diagnose gallstone disease

Point-of-care ultrasound to diagnose gallstone disease
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October 2020

Rapid antigen detecting tests

Rapid antigen detecting tests for diagnosing group A streptococcal infections in the community pharmacy setting.
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October 2020

Transcatheter aortic valve implantation

Transcatheter aortic valve implantation for the treatment of patients with severe symptomatic aortic stenosis who are at intermediate surgical risk.
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October 2020

Point of care haemolysis detection

Point of care haemolysis detection in blood samples that may be deemed unfit for laboratory analysis.
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July 2020

Autologous haematopoietic stem cell transplantation

Autologous haematopoietic stem cell transplantation for previously treated, relapsing-remitting multiple sclerosis.
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July 2020

Cardiopulmonary exercise testing

Pre-operative cardiopulmonary exercise testing for people in whom major abdominal surgery is planned.
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May 2020

Remote blood glucose monitoring

Remote monitoring of blood glucose in women with gestational diabetes.
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May 2020

Tests to inform COVID-19 diagnosis

This is a report on the effectiveness of tests that detect SARS-CoV-2 virus or antibodies to SARS-CoV-2, to inform COVID-19…
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March 2020

Single-operator per-oral cholangioscopy

Single-operator per-oral cholangioscopy for the management of hepatobiliary-pancreatic disorders.
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December 2019

Occipital nerve stimulation

Occipital nerve stimulation for medically refractory chronic cluster headache.
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October 2019

Continuous Glucose Monitoring in Pregnancy

Continuous glucose monitoring systems for managing diabetes in pregnant women.
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October 2019

Pharmacogenetic testing

Pharmacogenetic testing to identify the risk of adverse reactions to anti-epileptic medications.
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May 2019

Hand-held ultrasound devices

Hand-held ultrasound devices for cardiac assessment and diagnosis of heart failure, in the community or primary care setting.
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March 2019

Synovasure® Alpha Defensin Lateral Flow Test Kit

Synovasure® Alpha Defensin Lateral Flow Test Kit for the assessment of periprosthetic joint infection.
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February 2019

Faecal immunochemical test-based prediction tools

Faecal immunochemical test-based prediction tools for the assessment of people presenting to primary care with symptomatic bowel disease.
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January 2019

Fluorine- or gallium- prostate-specific membrane antigen positron emission tomography radiotracers

Fluorine- or gallium- prostate-specific membrane antigen (PSMA) positron emission tomography (PET) radiotracers in the investigation of recurrent prostate cancer.
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June 2018

Point-of-care procalcitonin testing

Health Technology Wales researchers searched for evidence on the clinical and cost effectiveness of point-of-care procalcitonin testing in the assessment…
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April 2018

Sacral nerve stimulation

Sacral nerve stimulation to treat faecal incontinence that cannot be controlled with conservative management
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February 2018

Mechanical chest compression

Mechanical chest compression for use by the ambulance service to treat adults with out-of-hospital non-traumatic cardiac arrest.
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