Completed and ongoing appraisals topics are listed below. Topics that were not accepted onto the appraisal work programme are also listed with the Topic Exploration Report (these do not include Evidence Appraisal Reports or guidance). Learn more about our appraisal process here.

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September 2023

Control contact lenses and spectacles

Control contact lenses and spectacles for the treatment of myopia in children
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June 2023

Wearable cardioverter defibrillators

Wearable cardioverter defibrillators for people at risk of cardiac death
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March 2023

Photobiomodulation

Photobiomodulation for the prevention and treatment of oral mucositis associated with cancer treatment
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December 2022

Virtual reality distraction therapy

Virtual reality therapy for the management of procedure-related pain.
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November 2022

Continuous topical oxygen therapy

Continuous topical oxygen therapy to treat people with chronic non-healing and complex diabetic foot ulcers
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October 2022

Left atrial appendage occlusion in patients with atrial fibrillation

Left atrial appendage occlusion in patients with atrial fibrillation
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July 2022

Outpatient laryngeal biopsy

Laryngeal biopsies in the outpatient setting in people with suspected head and neck dysplasia/cancer
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June 2022

Stereotactic ablative radiotherapy (SABR)

Stereotactic ablative radiotherapy (SABR) for the treatment of renal cell carcinoma
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May 2022

Video laryngoscopes

Video laryngoscopes for use in pre-hospital care.
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May 2022

Electronic blood management systems

Electronic blood management systems for blood transfusions
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May 2022

Extreme HypoFractionated Radiotherapy (EHFRT)

Extreme HypoFractionated Radiotherapy (EHFRT) for localised prostate cancer
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February 2022

Transcranial magnetic stimulation

Transcranial magnetic stimulation for the treatment of depression
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November 2021

Strategies for Relatives (START) intervention

Strategies for Relatives (START) intervention to improve the mental health of carers of people with dementia
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November 2021

Natriuretic peptides to rule-in and rule-out a diagnosis of acute heart failure

Natriuretic peptides to rule-in and rule-out a diagnosis of acute heart failure in adults in the emergency department setting
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September 2021

FreeStyle Libre flash glucose monitoring

FreeStyle Libre flash glucose monitoring for the management of diabetes.
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July 2021

Haemodialysis antimicrobial barrier caps (ClearGuard)

Antimicrobial barrier caps for use with haemodialysis catheter hubs to reduce catheter-related bloodstream infections.
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May 2021

Corneal cross-linking

Corneal crosslinking to treat adults and children with keratoconus
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May 2021

Point-of-care ultrasound to diagnose gallstone disease

Point-of-care ultrasound to diagnose gallstone disease
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October 2020

Rapid antigen detecting tests

Rapid antigen detecting tests for diagnosing group A streptococcal infections in the community pharmacy setting.
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October 2020

Transcatheter aortic valve implantation

Transcatheter aortic valve implantation for the treatment of patients with severe symptomatic aortic stenosis who are at intermediate surgical risk.
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July 2020

Autologous haematopoietic stem cell transplantation

Autologous haematopoietic stem cell transplantation for previously treated, relapsing-remitting multiple sclerosis.
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July 2020

Cardiopulmonary exercise testing

Pre-operative cardiopulmonary exercise testing for people in whom major abdominal surgery is planned.
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March 2020

Single-operator per-oral cholangioscopy

Single-operator per-oral cholangioscopy for the management of hepatobiliary-pancreatic disorders.
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December 2019

Occipital nerve stimulation

Occipital nerve stimulation for medically refractory chronic cluster headache.
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December 2019

Multigrip upper limb prosthetics

Multi-grip myoelectric upper-limb prosthetics.
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October 2019

Continuous Glucose Monitoring in Pregnancy

Continuous glucose monitoring systems for managing diabetes in pregnant women.
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September 2019

Robot-assisted thoracic surgery

Robot-assisted thoracic surgery.
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May 2019

Hand-held ultrasound devices

Hand-held ultrasound devices for cardiac assessment and diagnosis of heart failure, in the community or primary care setting.
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March 2019

Synovasure® Alpha Defensin Lateral Flow Test Kit

Synovasure® Alpha Defensin Lateral Flow Test Kit for the assessment of periprosthetic joint infection.
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February 2019

Faecal immunochemical test-based prediction tools

Faecal immunochemical test-based prediction tools for the assessment of people presenting to primary care with symptomatic bowel disease.
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January 2019

Fluorine- or gallium- prostate-specific membrane antigen positron emission tomography radiotracers

Fluorine- or gallium- prostate-specific membrane antigen (PSMA) positron emission tomography (PET) radiotracers in the investigation of recurrent prostate cancer.
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April 2018

Sacral nerve stimulation

Sacral nerve stimulation to treat faecal incontinence that cannot be controlled with conservative management
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February 2018

Mechanical chest compression

Mechanical chest compression for use by the ambulance service to treat adults with out-of-hospital non-traumatic cardiac arrest.
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