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Completed and ongoing appraisals topics are listed below. Topics that were not accepted onto the appraisal work programme are also listed with the Topic Exploration Report (these do not include Evidence Appraisal Reports or guidance). Learn more about our appraisal process here.

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October 2021

Wiresafe

Wiresafe device to prevent guidewire retention during central venous catheter placement
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October 2021

At-home use of tablet computers to assist diagnosis and management of dementia

At-home use of tablet computers to assist diagnosis and management of dementia
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October 2021

Genetic prediction of cardiovascular risk (GenInCode)

Genetic risk prediction tools for prediction of onset of cardiovascular disease and prediction of recurrence of cardiovascular events.
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September 2021

Faecal Calprotectin Home Testing

Faecal calprotectin home testing for people with a confirmed diagnosis of inflammatory bowel disease
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September 2021

Simplified continuous EEG (cEEG) monitoring systems

Simplified continuous EEG (cEEG) monitoring systems for patients with neurological insults in critical care
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September 2021

WoundExpress – thigh administered intermittent pneumatic compression device

WoundExpress intermittent pneumatic compression device in people with hard-to-heal lower leg ulcers
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September 2021

TYRX Absorbable Antibacterial Envelope

TYRX Absorbable Antibacterial Envelope for patients at risk of cardiac implantable electronic device migration, erosion and infection
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September 2021

Automated oxygen titration (FreeO2 system)

Automated oxygen titration/administration systems for hospitalised patients who require oxygen
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September 2021

Catheter valves

Catheter valves to reduce urinary catheter complications
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September 2021

Parkinson’s KinetiGraph

Parkinson's KinetiGraph to monitor symptoms of Parkinson's disease
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September 2021

Full body cryotherapy

Full body cryotherapy for symptom reduction in people with fibromyalgia
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September 2021

PROMOGRAN™ Protease Modulating Matrix and PROMOGRAN PRISMA™ Wound Balancing Matrix

Oxidized regenerated cellulose and collagen (ORC-collagen) matrix wound dressings for chronic venous leg ulcers or diabetic foot ulcers
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September 2021

Trans-nasal endoscopy

Transnasal endoscopy for diagnosis of gastrointestinal cancers
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September 2021

Trans-abdominal ultrasound examination

Trans-abdominal ultrasound examination for gallbladder polyps
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September 2021

3D printed patient-specific implants

3D printed patient-specific implants in cranial neurosurgery and craniomaxillofacial surgery
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September 2021

Cryotherapy ablation interventions

Cryotherapy ablation interventions for the treatment of oesophageal conditions
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September 2021

Subepidermal moisture (SEM) scanners

Subepidermal moisture scanners for prevention of pressure ulcers
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September 2021

Blood-based liquid biopsies

Blood-based liquid biopsies for the diagnostic triaging of symptomatic males with suspected prostate cancer.
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September 2021

Sensor devices in falls prevention

Sensor devices for fall prevention in hospitalised patients
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September 2021

Prostatic urethral temporary implant insertion

Prostatic urethral temporary implant insertion for lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)
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September 2021

FreeStyle Libre flash glucose monitoring

FreeStyle Libre flash glucose monitoring for the management of diabetes.
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July 2021

Haemodialysis antimicrobial barrier caps (ClearGuard)

Antimicrobial barrier caps for use with haemodialysis catheter hubs to reduce catheter-related bloodstream infections.
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May 2021

Intraoperative radiotherapy (Xoft system)

Intraoperative radiotherapy for the treatment of brain tumours or brain metastases
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May 2021

Predictive monitoring for hypotension (Acumen IQ sensor/Acumen Hypotension Prediction Index software)

Predictive monitoring for hypotension in high risk patients during surgery and in critical care
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May 2021

Handheld single lead electrocardiogram devices

Handheld single lead electrocardiogram devices to detect atrial fibrillation in older adults and those with intermittent episodes
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May 2021

Normothermic machine perfusion (OrganOx metra)

Normothermic machine perfusion prior to liver transplantation.
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May 2021

Pillow speakers for tinnitus

Pillow speakers to deliver sound therapy for people with tinnitus
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May 2021

Home blood pressure monitoring

Home blood pressure monitoring for diagnosis of hypertension
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May 2021

Chlorhexidine-based meatal cleansing (Hexicath)

Chlorhexidine-based meatal cleansing prior to catheter insertion.
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May 2021

Oscillating positive expiratory pressure devices

Oscillating positive expiratory pressure devices for airway clearance in chronic hypersecretory lung conditions.
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May 2021

Extracorporeal shockwave therapy

Extracorporeal shockwave therapy for the treatment of musculoskeletal conditions.
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May 2021

Antimicrobial treatments for medical masks or personal protective equipment

Antimicrobial treatments for medical masks or personal protective equipment to reduce respiratory disease transmission
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May 2021

Corneal cross-linking

Corneal crosslinking to treat adults and children with keratoconus
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May 2021

Point-of-care ultrasound to diagnose gallstone disease

Point-of-care ultrasound to diagnose gallstone disease
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March 2021

Next generation sequencing for DLBCL classification

Next generation sequencing for DLBCL classification (HTG EdgeSeq DLBCL Cell of Origin Assay).
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March 2021

Pharyngeal electrical stimulation (Phagenyx)

Pharyngeal electrical stimulation for neurogenic dysphagia
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February 2021

Point-of-care test for acute respiratory infection

FebriDx point-of-care test for acute respiratory infection in patients attending Emergency Departments.
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December 2020

Radiofrequency-induced thermochemotherapy

Radiofrequency-induced thermochemotherapy for the treatment of non-muscle-invasive bladder cancer.
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October 2020

Rapid antigen detecting tests

Rapid antigen detecting tests for diagnosing group A streptococcal infections in the community pharmacy setting.
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October 2020

Transcatheter aortic valve implantation

Transcatheter aortic valve implantation for the treatment of patients with severe symptomatic aortic stenosis who are at intermediate surgical risk.
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October 2020

Point-of-care haemolysis detection

Point-of-care haemolysis detection in blood samples that may be deemed unfit for laboratory analysis.
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October 2020

Rapid fully-automated EGFR testing (Idylla)

Rapid fully-automated PCR testing (Idylla) to screen for EGFR mutational status in people with lung cancer.
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October 2020

Rapid fully-automated BRAF testing (Idylla)

Rapid fully-automated PCR testing (Idylla) to screen for BRAF mutational status in people with melanoma.
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September 2020

Digital triage platforms

Digital triage platforms for use in emergency or urgent care settings.
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July 2020

Autologous haematopoietic stem cell transplantation

Autologous haematopoietic stem cell transplantation for previously treated, relapsing-remitting multiple sclerosis.
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July 2020

Cardiopulmonary exercise testing

Pre-operative cardiopulmonary exercise testing for people in whom major abdominal surgery is planned.
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July 2020

Cytokine adsorbers

Cytokine adsorbers for the treatment of cytokine storm in people with severe coronavirus infection.
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June 2020

Virtual reality group therapy

Virtual reality as a tool to facilitate virtual group therapy support clinics or group psychological support.
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June 2020

Point-of-care lung ultrasound

Point-of-care lung ultrasound imaging for suspected and confirmed cases of COVID-19.
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May 2020

Gown safety

Safety of personal protective equipment gowns for health and social care workers.
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May 2020

Virtual reality exercise therapy

Virtual reality for exercise plan management.
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May 2020

Remote blood glucose monitoring

Remote monitoring of blood glucose in women with gestational diabetes.
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May 2020

Tests to inform COVID-19 diagnosis

This is a report on the effectiveness of tests that detect SARS-CoV-2 virus or antibodies to SARS-CoV-2, to inform COVID-19…
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May 2020

Convalescent Plasma Therapy

Convalescent plasma therapy for patients with COVID-19.
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May 2020

Hydrogen peroxide vapour

Hydrogen peroxide vapour to reprocess single-use personal protective equipment.
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April 2020

HemaClear exsanguination tourniquet

HemaClear exsanguination tourniquet to provide a bloodless surgical field during limb surgery.
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April 2020

Virtual examinations (sexual health)

Virtual examination of patients requiring sexual health services.
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March 2020

ResAppDx-EU smartphone app

Point-of-care smartphone applications (ResAppDx-EU) for the diagnosis of acute respiratory disease.
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March 2020

Single-operator per-oral cholangioscopy

Single-operator per-oral cholangioscopy for the management of hepatobiliary-pancreatic disorders.
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March 2020

Self-help IT tools

Digital self-help tools for mental health and wellbeing in children and young people.
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March 2020

Interpreter on Wheels and Interpreter now – deaf mental health services

Video remote interpreting and video relay services for deaf people with mental health problems.
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March 2020

Primary Care Audiology

Primary care audiology for people with ear or hearing-related symptoms.
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March 2020

CANTAB (Cambridge Neuropsychological Test Automated Battery) Mobile

Use of CANTAB Mobile in patients of all ages.
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March 2020

Insulin pumps

Continuous subcutaneous insulin infusion (CSII or ‘insulin pumps’) for people with type 1 and gestational diabetes.
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March 2020

Mental Health Triage System

Mental health triage scale as a prioritisation tool.
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March 2020

Teleopthalomology in acute setting

Teleophthalmology to diagnose acute eye problems.
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March 2020

PocketMedic app

PocketMedic as an education tool for people with chronic conditions.
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March 2020

Stroke rehabilitation using digital devices

Hand-held electronic devices for stroke rehabilitation.
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March 2020

Remote microphones (children)

Remote microphones and wireless streaming devices for use with hearing aids and cochlear implants in children with hearing loss.
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March 2020

Hemosep cell salvage technology

Hemosep for cell salvage during surgery.
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February 2020

Zephyr

Zephyr Endobronchial Valve (EBV) System for patients with severe or very severe emphysema.
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February 2020

Brain in Hand

Brain in Hand digital support system for people with neurological and mental health conditions.
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February 2020

Remote microphones (adults)

Remote microphone hearing assistance technology for improving speech recognition by hearing impaired adults.
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January 2020

Low carb program

Low carb program behaviour platform in people with type 2 diabetes, prediabetes and obesity.
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January 2020

Smartphone urinalysis

Smartphone-based urinalysis for users to self-test at home, using a test kit and mobile app.
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January 2020

Tomo

Tomo for common or low-severity mental health problems related to anxiety, depression and stress.
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January 2020

Aspire

Aspire for opportunistic identification of osteoporotic vertebral fragility fractures from computed tomography scans.
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January 2020

Endovascular procedures

Endovascular procedures compared with current standard of care.
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December 2019

Occipital nerve stimulation

Occipital nerve stimulation for medically refractory chronic cluster headache.
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November 2019

GENOTIME Project

GENOTIME Project for the diagnosis of intellectual disability/developmental delay.
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November 2019

Extreme hypo fractionation with biodegradable rectal spacer insertion

Extreme hypo fractionation combined with biodegradable rectal spacer insertion for prostate cancer radiotherapy.
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November 2019

VIVID

Video-supported informed consent for patients undergoing image-guided interventions.
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November 2019

Transfusion patient education

Methods and formats of delivering patient information about blood transfusion.
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November 2019

WaitLess App

WaitLess app for directing patients to minor injuries care.
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November 2019

Wales Automating Complexity Combating Infection

Machine learning and artificial intelligence approaches for reading microbiology request forms.
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November 2019

Digital communication platforms

Digital communication platforms to deliver speech and language therapy for children with speech sound disorders.
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November 2019

Pop2Hop

An app to support a daily programme of rehabilitation for patients with Achilles tendon rupture.
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November 2019

E-learning programme: Byw Bywyd Gyda Phoen

Digital self-management programmes for patients with chronic pain.
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November 2019

Project CHEETAH

Interactive programmes of care pathway management.
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November 2019

Integrated Facilities Management Systems

Integrated Facilities Management Systems for managing facility services in hospitals.
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November 2019

SMART infusion pumps

The use of SMART infusion pumps for improved drug infusion practice.
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November 2019

GENESIS Project

Genetic screening for fetal abnormalities in suspected miscarriages.
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November 2019

Let’s talk About Porphyria

Let’s talk About Porphyria: A virtual assistant that provides information to people with porphyria.
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October 2019

Continuous Glucose Monitoring in Pregnancy

Continuous glucose monitoring systems for managing diabetes in pregnant women.
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October 2019

Pharmacogenetic testing

Pharmacogenetic testing to identify the risk of adverse reactions to anti-epileptic medications.
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October 2019

Topical oxygen wound therapy

Continuous topical oxygen therapy to promote wound healing.
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September 2019

Lantum

Lantum workforce management system.
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September 2019

Insulin injection ports

Injection ports for the subcutaneous administration of insulin in people with diabetes.
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September 2019

Remote ECG Interpretation (ambulatory testing in the community)

Remote electrocardiogram (ECG) interpretation consultancy services to aid diagnosis and decision making in the primary care setting.
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September 2019

Ultralinq

Ultralinq picture archiving and communications system (PACS) in cardiology.
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