Skip to content

Completed and ongoing appraisals topics are listed below. Topics that were not accepted onto the appraisal work programme are also listed with the Topic Exploration Report (these do not include Evidence Appraisal Reports or guidance). Learn more about our appraisal process here.

A graphic representing a Topic Exploration Report

October 2025

Nitric oxide-generating wound dressings

Nitric oxide-generating wound dressings for diabetic foot ulcers
Read more
A graphic representing a Topic Exploration Report

October 2025

Point-of-care portable, digital endoscopes

Point-of-care portable, digital endoscopes for people with lower gastrointestinal (GI) symptoms in primary care
Read more
A graphic representing a Topic Exploration Report

October 2025

Epileptic seizure alarms

Wearable technologies and bed/mattress alarms for the detection of epileptic seizures
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

October 2025

Digital interventions for chronic kidney disease

Digital rehabilitation and self-management interventions for chronic kidney disease.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

October 2025

At-home video monitoring for epilepsy

At-home video monitoring for the diagnosis and management of epilepsy
Read more
A graphic representing a Topic Exploration Report

October 2025

Carer passport schemes

Carer passport schemes to identify and offer support, benefits and resources to carers.
Read more
A graphic representing a Topic Exploration Report

October 2025

Oral neuromuscular training devices for the treatment of dysphagia

Oral neuromuscular training devices for the treatment of dysphagia
Read more
A graphic representing a Topic Exploration Report

October 2025

Haemodialysis at home

Portable home dialysis systems
Read more
A graphic representing a Topic Exploration Report

October 2025

Digital population health management and risk stratification tools

Digital population health management and risk stratification tools
Read more
A graphic representing a Topic Exploration Report

October 2025

Oral neuromuscular training devices for the treatment of hiatus hernia or reflux

Oral neuromuscular training devices for the treatment of hiatus hernia or reflux
Read more
A graphic representing a Topic Exploration Report

August 2025

Salvage high dose rate brachytherapy (HDR-BT)

Salvage high dose rate brachytherapy (HDR-BT) for localised relapse of prostate cancer after prior curative intent radiotherapy.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

August 2025

Long length peripheral intravenous catheters

Long length peripheral intravenous catheters for patients with difficult intravenous access
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

August 2025

Photoplethysmography for the management of atrial fibrillation

Photoplethysmography for the management of atrial fibrillation
Read more
A graphic representing a Topic Exploration Report

July 2025

Electroencephalogram neurofeedback systems

Electroencephalogram neurofeedback systems for chronic pain
Read more
A graphic representing a Topic Exploration Report

July 2025

Cone-beam breast computed tomography

Cone-beam computed tomography for breast imaging.
Read more
A graphic representing a Topic Exploration Report

July 2025

Inherited cancer registries

Registries for the identification, tracking and surveillance of people at risk of inherited cancers
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

July 2025

Implantable tibial neuromodulation devices

Implantable tibial neuromodulation devices for treatment of urge urinary incontinence
Read more
A graphic representing a Topic Exploration Report

June 2025

Digital tools incorporating cognitive eye vergence markers to diagnose attention deficit hyperactivity disorder (ADHD) in adults and children

BGaze Clinic by BrainGaze is a computerised ADHD assessment. It takes 12 minutes to complete and involves using an eye…
Read more
A graphic representing a Topic Exploration Report

June 2025

Raman spectroscopy blood tests

Raman spectroscopy blood test combined with machine learning to identify colorectal cancer
Read more
A graphic representing a Topic Exploration Report

June 2025

AI-assisted pathology for gastric cancer biopsies

AI-assisted pathology to triage suspected gastric cancer biopsies
Read more
A graphic representing a Topic Exploration Report

June 2025

Artificial intelligence-assisted ultrasound

Artificial intelligence-assisted ultrasound for the detection of deep vein thrombosis
Read more
A graphic representing a Topic Exploration Report

June 2025

Online adaptive radiotherapy

Online adaptive radiotherapy in the treatment of cancer
Read more
A graphic representing a Topic Exploration Report

June 2025

Probiotic cleaning products

Probiotic cleaning products to reduce health-care associated infections in hospital settings
Read more
A graphic representing a Topic Exploration Report

June 2025

Smartwatches for atrial fibrillation

Smartwatches for the detection of atrial fibrillation
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

May 2025

Advanced electrosurgical bipolar vessel sealing systems during hysterectomy

Use of advanced electrosurgical bipolar vessel sealing systems during hysterectomy compared to other methods for control of bleeding.
Read more
A graphic representing a Topic Exploration Report

May 2025

AMBLor

AMBLor for identifying low-risk non-ulcerated early-stage cutaneous melanomas
Read more
Person typing on laptop

April 2025

Superior rectal artery embolisation for haemorrhoids

Superior rectal artery embolisation for the treatment of haemorrhoids.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

April 2025

Permanent implant brachytherapy devices for unresectable pancreatic cancer

Permanent implant brachytherapy devices for the treatment of locally advanced, unresectable pancreatic cancer
Read more
Person typing on laptop

April 2025

Point-of-care blood glucose monitoring systems for hypoglycaemia in neonates

Point-of-care blood glucose monitoring systems for diagnosis and management of hypoglycaemia in neonates
Read more
A graphic representing a Topic Exploration Report

April 2025

Gender affirming surgery

Gender affirming surgery for trans people
Read more
Person typing on laptop

April 2025

Leadless cardiac pacemakers

Leadless cardiac pacemakers for bradyarrhythmia
Read more
A graphic representing an Evidence Appraisal

April 2025

PrecivityAD blood test

PrecivityAD blood test for the assessment of Alzheimer’s Disease
Read more
A graphic representing a Topic Exploration Report

April 2025

AI assisted review of chest x-ray and CT scans

AI assisted review of chest x-ray and CT scans in the diagnosis of lung cancer
Read more
A graphic representing a Topic Exploration Report

March 2025

Tumour-profiling tests to guide treatment of breast cancer

Tumour-profiling tests to guide adjuvant-bisphosphonate treatment in early breast cancer.
Read more
A graphic representing a Topic Exploration Report

March 2025

Multiparametric magnetic resonance imaging

Multiparametric magnetic resonance imaging compared with biparametric magnetic resonance imaging for the detection of prostate cancer
Read more
A graphic representing a Topic Exploration Report

March 2025

Telemetric intracranial pressure monitoring

Long-term telemetric intracranial pressure monitoring for diagnosis and treatment optimisation of neurological conditions
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

January 2025

Catheter locking solutions

Non antibiotic antimicrobial anticoagulant catheter locking solutions for the prevention of catheter related complications
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

December 2024

Digital tools for diabetes management

Digital platforms for personalised diabetes management, education and support in adults
Read more
A graphic representing a Topic Exploration Report

December 2024

Artificial intelligence-assisted mammography reading (FxMammo)

Artificial intelligence-assisted mammography reading in the detection of breast cancer (FxMammo)
Read more
A graphic representing a Topic Exploration Report

December 2024

Body-worn sensor monitoring

Body-worn sensor monitoring for people receiving inpatient mental health services.
Read more
A graphic representing a Topic Exploration Report

December 2024

Non-contact, room-based monitoring

Non-contact, room-based monitoring for people receiving inpatient mental health services
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

December 2024

Robot-assisted benign gynaecological surgery

Robot assisted benign gynaecological surgery
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

December 2024

ELF test (Enhanced Liver Fibrosis)

The Enhanced Liver Fibrosis test for diagnosing advanced fibrosis in metabolic dysfunction-associated steatotic liver disease.
Read more
A graphic representing a Topic Exploration Report

November 2024

Capsule sponge devices

Capsule sponge devices to detect Barrett’s oesophagus and early-stage oesophageal cancer.
Read more
A graphic representing a Topic Exploration Report

November 2024

Hybrid Convergent ablation

Hybrid Convergent ablation for the treatment of atrial fibrillation
Read more
A graphic representing a Topic Exploration Report

November 2024

Anti-ligature products and devices

Anti-ligature products and devices to reduce suicide and self-harm.
Read more
A graphic representing a Topic Exploration Report

November 2024

PocDoc

PocDoc digital point-of-care cholesterol testing for cardiovascular disease risk assessment and management.
Read more
A graphic representing a Topic Exploration Report

November 2024

Contactless photoplethysmography using smart devices

Contactless photoplethysmography for measuring blood pressure using cameras on smart phones or tablets and artificial intelligence software.
Read more
A graphic representing a Topic Exploration Report

November 2024

Gastroelectrical stimulation for the treatment of gastroparesis

Gastroelectrical stimulation for the treatment of adults with severe, intractable gastroparesis.
Read more
A graphic representing a Topic Exploration Report

November 2024

Thermal ablation of colorectal liver metastases

Thermal ablation of liver metastases in people with colorectal cancer.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

November 2024

Advanced paramedic practitioners

Advanced paramedic practitioners for assessment and treatment of medical emergencies
Read more
A graphic representing a Topic Exploration Report

September 2024

Leakage notification systems for stoma care

Systems to warn people of leakage before it seeps beyond the stoma baseplate.
Read more
A graphic representing a Topic Exploration Report

August 2024

Linus Health Core Cognitive Evaluation digital assessment

Linus Health Core Cognitive Evaluation digital assessment to detect cognitive impairment.
Read more
A graphic representing a Topic Exploration Report

August 2024

Virtual reality as a psychological intervention

Virtual reality interventions to support people with mental health difficulties and/or neurodevelopmental conditions.
Read more
A graphic representing a Topic Exploration Report

August 2024

Auditory verbal therapy

Auditory verbal therapy for young children who are deaf and hard of hearing.
Read more
A graphic representing a Topic Exploration Report

August 2024

Perineal and pelvic rehabilitation

Perineal and pelvic rehabilitation for the prevention and treatment of anorectal dysfunction, pelvic organ prolapse and perineal pain in women.
Read more
A graphic representing a Topic Exploration Report

August 2024

Deontics Cancer MDT solution

Deontics Cancer MDT solution to streamline and support multi-disciplinary team meetings.
Read more
A graphic representing a Topic Exploration Report

August 2024

Autologous blood microfiltration systems

Autologous blood microfiltration systems for peri- and post-operative cell.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

August 2024

Artificial intelligence assisted tools for prostate cancer diagnosis using whole slide biopsy images

Artificial intelligence assisted tools for prostate cancer diagnosis using whole slide biopsy images
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

July 2024

Floseal in the treatment of epistaxis

Floseal is a bioresorbable topical haemostatic agent which can be used in the treatment of epistaxis (nosebleeds) if first aid…
Read more
A graphic representing a Topic Exploration Report

July 2024

Hip protectors

Hip Protectors for users at risk of falls
Read more
A graphic representing a Topic Exploration Report

July 2024

Wearable wound care for hidradenitis suppurativa

Wearable wound care for hidradenitis suppurativa
Read more
A graphic representing a Topic Exploration Report

July 2024

AI prediction of fatty liver disease from laboratory test results

Artificial intelligence-interpretation of laboratory test results to predict fatty liver disease in primary care.
Read more
A graphic representing a Topic Exploration Report

July 2024

Interventions to prevent and reduce gang-related violence

Interventions to prevent and reduce gang-related violence in children and young adults.
Read more
A graphic representing a Topic Exploration Report

July 2024

National Early Warning Score systems in acute care

National Early Warning Score systems (NEWS and NEWS2) for adult patients across the acute care pathway.
Read more
A graphic representing a Topic Exploration Report

July 2024

Wire-Free, Nonradioactive Localisation Techniques

Wire-Free, Nonradioactive Localisation Techniques to Guide Surgical Excision of Nonpalpable Breast Tumours.
Read more
A graphic representing a Topic Exploration Report

July 2024

Store-and-forward teledermatology

Store-and-forward teledermatology for triage of primary care referrals
Read more
A graphic representing a Topic Exploration Report

July 2024

Fibrin sealants for intraoperative bleeding

Fibrin sealants as a means to control bleeding in surgical procedures
Read more
A graphic representing a Topic Exploration Report

July 2024

Pulsed field ablation for atrial fibrillation

Pulsed field ablation for atrial fibrillation.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

July 2024

AI-assisted endoscopy for gastrointestinal cancer

Artificial Intelligence (AI)-assisted endoscopy in the detection of gastrointestinal cancer and pre-cancerous lesions
Read more
A graphic representing a Topic Exploration Report

June 2024

Pathway Through Pain: A digital technology for management of low back pain

Low back pain can be treated or managed using a wide range of interventions. Digital technologies, such as Pathway Through…
Read more
A graphic representing a Topic Exploration Report

May 2024

AI-assisted ECG interpretation

Artificial intelligence-assisted electrocardiogram interpretation for people with suspected cardiovascular disease in primary/emergency care
Read more
A graphic representing a Topic Exploration Report

May 2024

Video camera-assisted or electromagnetic placement of enteral feeding tubes

Video and electromagnetic-guided systems to assist in the placement of feeding tubes
Read more
A graphic representing a Topic Exploration Report

May 2024

Reinforced biologic mesh for hernia repair

Reinforced biologic mesh, consisting of both biologic and synthetic components, for use in hernia repair
Read more
A graphic representing a Topic Exploration Report

April 2024

Hearing aids to delay the onset or progression of dementia

Hearing aid provision to delay the onset or progression of dementia in people living with hearing loss
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

March 2024

Intensive Family Preservation Programmes (IFPP)

Intensive Family Preservation Programmes (IFPP) for families in crisis, where there is an imminent risk of out-of-home placement or children…
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

March 2024

Video feedback interventions

Video feedback interventions to improve communication within family relationships and support children at risk
Read more
A graphic representing a Topic Exploration Report

March 2024

Orthotic bracing for scoliosis

Orthotic bracing for the treatment of idiopathic scoliosis in children and young people
Read more
A graphic representing a Topic Exploration Report

March 2024

Slot-scanning, biplanar X-ray imaging (EOS imaging systems) for spine and lower limb conditions and orthopaedic surgery

Slot-scanning, biplanar X-ray imaging, such as EOS imaging systems, is a way of acquiring full body X-ray images using lower…
Read more
A graphic representing a Topic Exploration Report

March 2024

Community respiratory care services

Community based respiratory care services for people with chronic respiratory conditions
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

March 2024

Liposuction for the treatment of chronic lymphoedema

Liposuction for the treatment of chronic lymphoedema
Read more
A graphic representing a Topic Exploration Report

March 2024

Computer-assisted thermography for breast cancer screening (Thermalytix)

Computer-assisted diagnostic tools for thermographic images to assist in diagnosis of malignant breast lesions.
Read more
A graphic representing a Topic Exploration Report

March 2024

Artificial intelligence for the diagnosis of chronic obstructive pulmonary disease at point-of-care

N-Tidal Diagnose (TidalSense) combines a high-resolution carbon dioxide sensor with an artificial intelligence platform to measure changes in lung function…
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

January 2024

Digital wound management tools

Digital tools for the monitoring and management of wounds.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

January 2024

Low energy contact X-ray brachytherapy (CXB)

Low energy contact X-ray brachytherapy (CXB) for the treatment of early stage rectal cancer
Read more
A graphic representing a Topic Exploration Report

January 2024

Circulating tumour DNA tests for T790M mutations in non-small cell lung cancer

Circulating tumour DNA tests for T790M mutations in non-small cell lung cancer
Read more
A graphic representing a Topic Exploration Report

January 2024

Optical sensor devices for the detection of infiltration and extravasation of intravenous fluid

Optical sensor devices for the detection of infiltration and extravasation of intravenous fluid
Read more
A graphic representing a Topic Exploration Report

January 2024

Optical coherence tomography angiography for detection and diagnosis of vascular diseases of the eye

Optical coherence tomography angiography for detection and diagnosis of vascular diseases of the eye
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

January 2024

Robot-assisted thoracic surgery

Robot-assisted thoracic surgery.
Read more
A graphic representing a Topic Exploration Report and Evidence Appraisal

December 2023

Radiofrequency renal denervation

Renal denervation to treat people with resistant hypertension
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

December 2023

Solution-focused assessment tools

Solution-focused assessment tools for improving the treatment of people with severe mental illness within secondary mental health services.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

December 2023

Percutaneous implantation of pulmonary artery pressure sensors

Percutaneous implantation of pulmonary artery pressure sensors for monitoring treatment of chronic heart failure.
Read more
A graphic representing a Topic Exploration Report

December 2023

Automated pH testing to verify placement of nasogastric feeding tubes

Automated pH testing to verify placement of nasogastric feeding tubes
Read more
A graphic representing a Topic Exploration Report

December 2023

Clinical decision support software with integrated AI for the management of patients with incidental pulmonary nodules identified on chest CT scans (Optellum Virtual Node Clinic)

Clinical decision support software with integrated AI for the management of patients with incidental pulmonary nodules identified on chest CT…
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

November 2023

Multi-grip upper limb prosthetics

Multi-grip myoelectric upper-limb prosthetics.
Read more
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

September 2023

Myopia-control contact lenses and spectacles

Myopia-control contact lenses and spectacles to slow the progression of myopia in children and adolescents.
Read more
A graphic representing a Topic Exploration Report

September 2023

Digital cognitive assessment tools

Digital cognitive assessment tools to detect early-stage impairment caused by neurodegenerative disorders
Read more
A graphic representing a Topic Exploration Report

September 2023

Pre-emptive pharmacogenetic (PGx) testing using a multiple gene panel to guide treatment and reduce adverse drug reactions

Pre-emptive pharmacogenetic (PGx) testing using a multiple gene panel to guide treatment decisions
Read more
A graphic representing a Topic Exploration Report

September 2023

Hyperspectral imaging for the detection of cutaneous melanoma

Hyperspectral imaging for the detection of cutaneous melanoma
Read more
A graphic representing a Topic Exploration Report

September 2023

Photobiomodulation therapy for dry age-related macular degeneration

Use of near infrared spectrum light to in the treatment of dry age-related macular degeneration
Read more